Amphetam, The term ‘designer amphetamine’ is often used to describe synthetic chemicals that are derived from amphetamine or methamphetamine. Designer drugs are structural analogues of controlled substances that are designed to mimic the pharmacological effects of the parent drug while avoiding detection or categorization as illegal. Many of the older designer drugs (researchchemicals)are structural analogues of psychoactive tryptamines or phenethylamines but there are many other chemicallyunrelated new psychoactive substances that can be considered part of the designer drug group. Methylenedioxyphenethylamines (MDxx) are a large chemical class of derivatives of the phenethylamines, which includes many psychoactive drugs that act as entactogens, psychedelics, and/or stimulants, as well as entheogens. Amphetam Online Research Chemicals.